Gejala sipilis memiliki beberapa stadium infeksi Setelah seseorang terinfeksi dengan sipilis ada masa inkubasi yakni masa sampai timbulnya gejala luka terbuka yang umum disebut chancre yakni sekitar 9 sampai 90 hari dan biasanya pada 21 hari sudah dapat terlihat Gejala
sipilis pada wanita biasanya terjadi dalam empat stadium berbeda Stadium satu atau stadium awal Sipilis pada ( Baca Juga : Obat Sipilis Murah ) stadium ini ditandai dengan munculnya luka berwarna kemerahan dan basah di daerah vagina atau mulut Luka tersebut disebut chancre dan muncul pada bagian tubuh
tempat spirochaeta masuk ke dalam tubuh seseorang saat pertama kalinya Pembengkakan kelenjar getah bening juga biasa ditemukan pada stadium ini dan setelah beberapa minggu chancre tersebut akan menghilang dengan sendirinya Stadium inilah yang merupakan stadium paling rawan untuk menular Pada
stadium dua biasanya para penderita yang terkena sipilis akan mengalami ruam khususnya pada telapak kaki serta tangan Mereka juga dapat mengalami luka luka pada mulut bibir tenggorokan dubur atau anus serta vagina Gejala yang mirip dengan gejala flu seperti demam
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